Quantitative Pharmacology

Course description Quantitative Pharmacology
Year: 2018-2019
Catalog number: 4323QPHAR
  • Dr. C. van Hasselt
Language: English
Blackboard: Yes
EC: 4
Level: 500
Period: Semester 2, Block III
Hours of study: 50:00 hrs
  • Yes Elective choice
  • No Contractonderwijs
  • Yes Exchange
  • Yes Study Abroad
  • No Evening course
  • No A la Carte
  • No Honours Class

This information is without prejudice. Alterations can be made for next year.


This lecture series comprises the theoretical basis and application of quantitative pharmacology and pharmacokinetic-pharmacodynamic (PK-PD) modeling with the purpose of characterizing and predicting the onset, intensity, and duration of drug effects in patients.


Dr. J.G.C. van Hasselt (coen.vanhasselt@lacdr.leidenuniv.nl)

Admission requirements

Students of Bio-Pharmaceutical Sciences. Adequate knowledge of Pharmacology and Statistics.

Mode of Instruction

The course will mainly consist of lectures and group discussions. Active participation in the discussions and self-study skills are required for this course.

Reading list

Will be announced during the course.

Course objectives

• Understand key concepts inpharmacokinetics and pharmacodynamics processes and their description using pharmacokinetic-pharmacodynamic (PK-PD) models.
• Understand the basic mathematical principles used in PK-PD models.
• Understand the basic concepts in quantitative systems pharmacology.

Assessment method

Written Exam (75%), and assignments (25%).


The course is taught in March 2019.


Application via uSis. Registration closes 1 month before the start of the course.


A minimum of 5 participants is required.